In addition to the usual Hollywood celebs with new movies, TV shows, songs and books to promote, he'll also have more than his share of political guests, so you can look forward to a mix of Scarlett Johansson, Lupita Nyong'o, Amy Schumer, Emily Blunt, Jake Gyllenhaal, Stephen King, Senator Jeb Bush and Senator Bernie Sanders, to name but a few.
These irreverent billboards heralding his Late Show debut were first snapped along Pico Boulevard on August 12, then along Santa Monica Boulevard, La Cienega Boulevard, Fairfax Avenue, Beverly Boulevard and La Brea Avenue through September 7, 2015.
Here's also a bonus billboard blast from the past, when Stephen Colbert and Jon Stewart were providing Presidential Election commentary on Comedy Central, snapped along the Sunset Strip in October 2012.
Good luck Stephen, and after the rest of you have checked out his debut hosting gig tonight, be sure to come back all this week for more fun new TV show billboards filling the L.A. skyline.
UPDATED: Here's also a creative Daily Billboard didn't spy in L.A., but spotted in New York City on November 3, 2015. Stephen Colbert certainly seems to be a fan of the pointing finger.
UPDATED: In addition here's a recycled ad creative to help elicit 2016 Emmy consideration for The Late Show, snapped along Santa Monica Boulevard in West Hollywood on May 10, 2016.